The US population is aging fast, with 56 million people over 65 years, approximately 16.9% of the population. As the trend continues, seniors are likely to outnumber children by 2034. With old age comes physical, cognitive, and emotional decline; of course, you get closer to the end.
While the aging process is complicated, declining NAD+ levels (nicotinamide adenine dinucleotide) play a vital role in accelerating aging, organ dysfunction, and disease. Boosting NAD+ levels with NMN supplements can delay aging and keep people healthier for longer. However, there are concerns about NMN’s benefits, safety, and potential side effects.
In this guide, we highlight all you need to know about the benefits of NMN, its potential side effects, and how to tackle them.
NMN, Aging, and Longevity
You may wonder what NMN is, how it relates to aging and longevity, and whether there are any NMN side effects. NMN is an acronym for Nicotinamide mononucleotide, a naturally-produced molecule in the body that helps with cellular energy production and DNA repair.
It also generates NAD+, an essential molecule promoting cellular and metabolic functions, ensuring cells and organs stay healthy.
As people age, NAD+ levels drop substantially. In fact, by 50 years, you have half of the NAD+ levels you had at 20. Where does NMN come in? While you can directly raise NAD+ in the body, research shows that NMN is more effective in alleviating age-related conditions and enhancing health and longevity markers.
NMN has an excellent safety profile and numerous health benefits, such as enhancing cardiovascular health, lowering inflammation, and enhancing cognitive function. When it comes to aging, NMN is helpful in the following ways;
Promotes cell recovery and growth: NMN supplies energy to the aging cells so they function optimally. A study published in the Nature Metabolism journal revealed that NMN can be delivered directly to cells for cellular fuel production.
Reduce metabolic diseases: Older people have a high risk for metabolic diseases like obesity, diabetes, and dyslipidemia, and NMN is handy in preventing them.
Reactive faltering blood flow, thus reducing age-related complications
Improve immunity: Clinical studies show that using NMN to increase NAD+ levels boosts the immune system, assisting the body in fighting infections and illnesses.
NMN’s Safety and Side Effects
Research on NMN, including its properties, benefits, and effects, is ongoing, with no identified side effects yet. So, typically, NMN is safe and well tolerated by most people, and a human trial in Japan confirmed this. In the study, ten healthy men took a single oral dosage of NMN.
No significant clinical symptoms were reported, and primarily biomarkers like blood pressure, heart rate, and body temperature were unchanged.
Similarly, Dr. David Sinclair, Times Magazine, ranks him as one of the 100 most influential people in the world, reports using NMN supplements for years without any harmful side effects. However, the doctor notes that appropriate storage is vital to prevent adverse reactions.
Animal studies have shown no side effects of NMN. In fact, rodent studies prove NMN’s positive impact on the body’s metabolism, immunity, and heart health. In a long-term rat study, NMN did not portray any severe effects or toxicity.
Identifying and Treating NMN Side Effects
Although NMN is generally safe, it can have a few side effects for some people, including;
Nausea
Headaches
Flushing
Gastrointestinal symptoms
Dizziness
Diarrhea
Identifying NMN side effects is easy, and you get the above symptoms a few hours after taking the supplements. Also, any strange feelings or discomfort after taking the supplements could signal an adverse reaction, though rare.
The best thing about NMN side effects is that they may subside with time as the body gets accustomed to the supplement. Also, keeping off NMN for some time –say a week can give your body a break and increase NMN effectiveness.
Nevertheless, see a doctor immediately if you experience persistent and severe side effects. Also, the doctor can clear you to take the supplement with medication for preexisting conditions.
Notably, using quality and pure NMN supplements is vital for the best results and to minimize side effects. Experts affirm that the quality of NMN affects its functioning, thus the need to buy the supplements from reputable and certified vendors.
NMN Side Effects with Dosage
Since NMN dosage research is still in its infancy, there is no optimal dosage to harness the most benefits. However, recent research suggests that taking between 250 and 2,000 mg of NMN is ideal and has the most physical and cognitive gains.
Common determinants of dosage include age, weight, and health status. An oral dose of 250 mg daily is sufficient for people aged 60 years and above.
Some people ask whether an overdose of NMN can cause adverse side effects. Due to the lack of adequate research, it is hard to give a conclusive answer. A Chinese study examined the effect of NMN on aerobic capacity that declines with age.
In the study, participants took up to 1200mg of NMN daily for six weeks, reporting that aerobic performance increased with the dose. As such, it can be deduced that high NMN doses can support older adults’ diminished physical function without significant side effects.
Conclusion
The thought of slowing down the aging is wild but welcome as the US population ages substantially. Turning back the hands of time is no longer fictional with NMN supplements which decelerate age-related disease and deterioration, promoting longevity and youthfulness.
NMN supplements counteract the age-related natural decline while improving cognitive function, heart health and strengthening immunity. NMN research is promising, making it a good supplement for many reasons, whether you are suppressing aging.
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